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中国大学MOOC医学生物化学与分子生物学（17版）_-成人教育作业答案

医学生物化学与分子生物学（17版）_-成人教育

学校: 九八五题库

学校: 超星学习通

题目如下：

1. 1. Which of the following glycolytic enzymes is used in gluconeogenesis?

A. Glucokinase

B. Phosphofructokinase 1

C. Pyruvate kinase

D. Aldolase

E. None of them

答案: Aldolase

2. 2. Which one of the following statements concerning glycolysis is correct?

A. The conversion of glucose to lactate requires the presence of oxygen.

B. Hexokinase is improtant in hepatic glucose metabolism only in the absorptive period following consumption of a carbohydrate-containing meal.

C. Fructose 2,6-bisphosphate is a potent inhibitor of phosphofructokinase.

D. The rate-limiting reactions are also the irreversible reaction.

E. The conversion of glucose to lactate yields two ATP and two NADH

答案: The rate-limiting reactions are also the irreversible reaction.

3. 3. Which one of the following is a condition decreased the oxidation of acetyl CoA by the citric acid cycle?

A. A low ATP/ADP ratio

B. A low NADH due to rapid oxidization to NAD+ through the respiratory chain

C. A low NAD+/NADH ratio

D. A high concentration of AMP

E. A low GTP/GDP ratio

答案: A low NAD+/NADH ratio

4. 4. Epinephrine and glucagon have which one of the following effects on glycogen metabolism in the liver?

A. The net synthesis of glycogen is increased.

B. Glycogen phosphorylase is activated, whereas glycogen synthase is inactivated.

C. Both glycogen phosphorylase and glycogen synthase are activated but at significantly different rates.

D. Glycogen phosphorylase is inactivated, whereas glycogen synthase is activated.

E. cAMP-dependent protein kinase is activated, whereas phosphorylase kinase is inactivated.

答案: Glycogen phosphorylase is activated, whereas glycogen synthase is inactivated.

5. 5. NADH is required for the one-step reaction by which pyruvate is converted to

A. oxaloacetate

B. acetyl CoA

C. phosphoenolpyruvate

D. lactate

E. none of them

答案: lactate

6. 6. The pentose phosphate pathway generates each of the following products EXCEPT

A. NADPH, which may be used for fatty acid synthesis

B. ribose 5-phosphate, which may be used for the biosynthesis of ATP

C. compounds that are intermediates of glycolysis

D. D.xylulose 5-phosphate by one of the nonoxidative reactions

E. glucose from ribose 5-phosphate and CO2

答案: glucose from ribose 5-phosphate and CO2

7. 7. The synthesis of glucose from pyruvate by gluconeogenesis:

A. occurs exclusively in the cytosol.

B. is inhibited by an elevated level of glucagon.

C. requires the participation of biotin.

D. involves lactate as an intermediate.

E. requires the oxidation/reduction of FAD.

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

8. 8. A two year-old boy was brought into the emergency room, suffering from severe fasting hypoglycemia. On physical examination, he was found to have hepatomegaly. Laboratory tests indicated that he also had hyperlacticacidemia and hyperuricemia. A liver biopsy indicated that hepatocytes contained greater than normal amounts of glycogen that was of normal structure. The child was subsequently found to be missing which of the following enzymes?

A. Glycogen synthase

B. Glycogen phosphorylase

C. Glucose 6-phosphatase

D. Amylo-α (1→ 6)-glucosidase

E. Amylo-α (1→ 4) → α (1→ 6)-transglucosylase

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

9. 9. Most of the reducing equivalents utilized for synthesis of fatty acids can be generated from

A. The pentose phosphate pathway

B. Glycolysis

C. The citric acid cycle

D. Mitochondrial malate dehydrogenase

E. Citrate lyase

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

10. 10. Which of the following metabolic pathway take place in the mitochondira?

A. A.glycolytic pathway

B. the synthesis of ketone body

C. pentose phosphate pathway

D. the synthesis of the fatty acid

E. the synthesis of the glycogen

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

11. 11. Which coenzyme in pyruvate dehydrogenase complex serves as the final hydrogens acceptor?

A. FAD

B. lipoate

C. NAD+

D. TPP

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

12. 12. The unique pathway for mature red blood cells to obtain ATP is

A. pentose phosphate pathway

B. tricarboxylic acid cycle

C. β-oxidation of fatty acid

D. glycolysis

E. gluconeogenesis

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

13. 13. Which enzyme is the key enzyme in glycogenolysis (glycogen degradation) ?

A. Phosphorylase

B. Hexokinase

C. Phosphoenol pyruvate carboxykinase

D. HMG-CoA reductase

E. Pyruvate kinase

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

14. 14. The principl function of the TCA cycle is to

A. generate CO2

B. transfer electrons from the acetyl portion of acetyl CoA to NAD+ and FAD

C. oxidize the acetyl portion of acetyl CoA to oxaloacetate

D. generate heat from the oxidation of the acetyl portion of acetyl CoA

E. dispose of excess pyruvate and fatty acids

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

15. 15. The compound which can not be converted into glucose is in animals.

A. lactate

B. pyruvate

C. glycerol

D. fatty acid

E. glycine

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

16. 16. The degradation of glycogen normally produces

A. more glucose than glucose l-phosphate

B. more glucose 1-phosphate than glucose

C. equal amounts of glucose and glucose 1-phosphate

D. neither glucose nor glucose l-phosphate

E. only glucose l-phosphate

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

17. 17. In which compartment of the cell does glycolysis occur?

A. Mitochondrion

B. Nucleus

C. Soluble cytoplasm (cytosol)

D. Rough endoplasmic reticulum

E. Smooth endoplasmic reticulum

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

18. 18. Which of the following statements about glycolysis is TRUE?

A. Glucokinase catalyzes the conversion of glucose to glucose 6-phosphate in the liver

B. Phosphofructokinase 1 catalyzes the conversion of fructose 1,6-bisphosphate to dihydroxyacetone phosphate

C. When one molecule of glucose is converted to pyruvate via glycolysis, one molecule of NADH is reduced

D. When one molecule of glucose is converted to pyruvate via glycolysis, one carbon is lost as CO2

E. Hexokinase catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

19. 19. An infant with an enlarged liver has a glucose 6-phosphatase deficiency. This infant

A. cannot maintain blood glucose levels either by glycogenolysis or by gluconeogenesis

B. can use liver glycogen to maintain blood glucose levels

C. can use muscle glycogen to maintain blood glucose levels

D. can convert both alanine and glycerol to glucose to maintain blood glucose levels

E. none of them

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

20. 20. How many net molecules of ATP are generated in the conversion of glucose to pyruvate?

A. 0

B. 1

C. 2

D. 3

E. 4

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

21. 1. What is the consequence of thermalgenin effect.

A. Producing more heat

B. ETC is inhibited

C. Producing more ATP

D. Oxidative phosphorylation is increased

E. None of the above

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

22. 2. Which of following subunit is mainly responsible to catalyze the synthesis of ATP in ATP synthase?

A. α

B. β

C. γ

D. ε

E. c

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

23. 3. 下列化合物中除( )外都是呼吸链的组成成分。

A. CoQ

B. Cytb

C. CoA

D. NAD+

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

24. 4. 关于生物氧化的描述哪一项是错误的？

A. 一系列酶参与催化

B. 反应条件较温和

C. CO2与反应物中的

D. 释放的能量部分储存在高能化合物中

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

25. 5. The electron transport chain is made up of four segments (Complexes I-IV with O2 as the final electron acceptor). Which statement best describes the electron transport chain

A. Each component involves a phosphorylation step.

B. Each complex directly transfers electrons to O2.

C. Electrons flow spontaneously from one carrier to the next.

D. Fe-S cluster acts as a important coenzyme in complex.

E. Locate in outer membrane of mitochondria

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

26. 6. A research was studying oxidative phosphorylation in a suspention of carefully washed and isolated mitochondria ATP, ADP, inorganic phosphate, lactate, lactate dehydrogenase, and oxygen were introduced to the suspension, and he was able to demonstrate ATP production within the mitochondria.The research we then added oligomycin to the mixture, which stopped oxygen uptake. This occurred due to which of the following?

A. Inhibition of complex Ⅰ

B. Inhibition of complex Ⅱ

C. Inhibition of complex Ⅲ

D. Inhibition of complex Ⅳ

E. Inhibition of the proton translocating ATPase

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

27. 7. Why does the oxidation of NADH lead to roughly 3 ATPs, while FADH2 oxidation produces only about 2 ATPs?

A. FADH2 enters the electron transport chain later than NADH.

B. The 2 hydrogens in FADH2 go directly to the synthesis of 2 ATPs.

C. More NADH is produced during metabolism.

D. FADH2 is only important in fatty acid oxidation.

E. Redox potential change is only sufficient for production of 2 ATPs.

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

28. 8. 线粒体中跨膜质子浓度梯度建立后是

A. 线粒体内膜内侧的质子浓度高于外侧的质子浓度

B. 线粒体内膜外侧的质子浓度高于内侧的质子浓度

C. 线粒体外膜内侧的质子浓度高于外侧的质子浓度

D. 线粒体外膜外侧的质子浓度高于内侧的质子浓度

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

29. 9. The electron transport chain is made up of four segments (Complexes I-IV with O2 as the final electron acceptor). Which statement best describes the electron transport chain?

A. Each component involves a phosphorylation step.

B. Each complex directly transfers electrons to O2.

C. Electrons flow spontaneously from one carrier to the next.

D. Every complex has a Fe-S cluster.

E. Locate in outer membrane of mitochondria

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

30. 10. 线粒体外NADH经α-磷酸甘油穿梭作用，进入线粒体内实现氧化磷酸化，其p/o值为

A. 0

B. 1.5

C. 2.5

D. 3.5

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

31. 1. In liver, large numbers of acetyl CoA derived from fat mobilization convert mainly into

A. glucoses

B. cholesterols

C. fatty acids

D. ketone bodies

E. cholesterol esters

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

32. 2. A 19-year-old man complains of “brown urine” and pain in the muscles of his arms and legs experienced while playing touch football. He has had several episodes of muscle pain during exercise, but he had not noticed darkening of his urine afterward. The pain usually resolved overnight. Physical examination reveals a well-fed male of normal stature. Reflexes and range of motion in all arms and legs are normal, but there is some paraparesis (weakness), especially in his right leg. A muscle biopsy is taken and sent for specialized resting. The patient is sent home with a recommendation to take a dietary carnitine supplement. Which of the following is the most likely diagnosis?

A. Medium-chain fatty acyl CoA dehydrogenase (MCAD) deficiency

B. Carnitine deficiency

C. Carnitine palmitoyltransferases I deficiency

D. Carnitine palmitoyltransferases II deficiency

E. Marfan syndrome

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

33. 3. Which is the following can transfer acetyl group from mitochondria to cytoplasm

A. Acetyl-CoA

B. Acetyl-carnitine

C. Succinate

D. Citric acid

E. Oxaloacetate

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

34. 4. You are examining a patient who exhibits fasting hypoglycemia and need to decide between a carnitine deficiency and a carnitine acyltransferase 2 deficiency as the possible cause. You order a blood test to specifically examine the levels of which one of the following?

A. Glucose

B. Ketone bodies

C. Insulin

D. Acyl-carnitine

E. Carnitine

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

35. 5. Synthesis of fatty acids occurs in the cytoplasm, and is catalyzed by fatty acid synthase. In animals, fatty acid synthase is a homodimer, with each chain approximately 250,000 Daltons in size. The two chains are linked head to tail. All of the components of fatty acid synthase, including acyl carrier protein (ACP) and β-ketoacyl ACP synthase, are contained within the two chains. Reactions occur in the space between the two chains, an arrangement that keeps the reactants in one place. The first round of synthesis produces a 4-carbon unit. From here, two carbons are added until the final product, palmitate is made. How many rounds does it take to make palmitate?

A. 14

B. 10

C. 7

D. 2

E. Cannot be determined

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

36. 6. The compound which can not be oxidized into CO2 and H2O in vivo is

A. acetoacetate

B. lactate

C. glycerol 3-phosphate

D. cholesterol

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

37. 7. The activated choline required for the lecithin biosynthesis is

A. ADP- choline

B. CDP- choline

C. GDP- choline

D. UDP- choline

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

38. 8. After they are produced from acetyl-CoA in the liver, ketone bodies are mainly used for which one of the following processes?

A. Excretion as waste products.

B. Energy generation in the liver.

C. Conversion to fatty acids for storage of energy.

D. Generation of energy in the tissues.

E. Generation of energy in red blood cells.

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

39. 9. Which one of the following statements concerning chylomicrons is CORRECT?

A. Chylomicrons are made inside intestinal cells and secreted into lymph, where they acquire apolipoproteins B and C.

B. The core of chylomicrons contains triacylglycerol and phospholipids.

C. The enzyme hormone sensitive lipase acts on chylomicrons to release fatty acids from triacylglycerol when they are bound to the surface of endothelial cells in blood capillaries.

D. Chylomicron remnants differ from chylomicrons in that they are smaller and contain a lower proportion of triacylglycerol.

E. Chylomicrons are taken up by the liver.

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

40. 10. A 7-year-old girl has 1 1-month history of foul-smelling diarrhea. Upon further inquiry, the frequency seems to be 4-6 stools per day. She has also had trouble seeing at night in the past2 weeks. Her WBC count is normal. Physical examination is entirely normal. Examination of a stool sample reveals that it is bulky and greasy. Analysis does not reveal any pathogenic microorganisms or parasites but confirms the presence of fats. Further evaluation of this patient would likely reveal which of the following conditions?

A. Lactose intolerance

B. Biliary insufficiency

C. Ileal disease

D. Diabetes

E. Giardiasis

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

41. 11. A patient presents in your office with very high levels of serum cholesterol. After a series of tests, you conclude that the patient has high circulating levels of LDL cholesterol, but has normal levels of the liver LDL receptor. One possible explanation for this observation is which of the following?

A. The patient has a mutated form of apoprotein B-100.

B. The inability to selectively remove cholesterol from the LDL complex.

C. The absence of the enzyme lipoprotein lipase.

D. Decreased levels of acyl-CoA: cholesterol acyltransferase

E. Altered phosphorylation of the LDL receptor.

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

42. 12. Under condition of starvation, the major fuel for the brain is

A. blood glucose

B. fatty acids

C. ketone bodies

D. amino acids

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

43. 13. Rate-limiting enzyme in the synthesis of ketone bodies is

A. thiolase

B. HMG-CoA synthase

C. HMG-CoA lyase

D. β-hydroxybutyrate dehydrogenase

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

44. 14. The class of drugs called statins have proved very effective against hypercholesterolemia, a major cause of atherosclerosis and associated cardiovascular disease. These drugs reduce plasma cholesterol levels by:

A. Preventing absorption of cholesterol from the intestine.

B. Increasing the excretion of cholesterol from the body via conversion to bile acids.

C. Inhibiting the conversion of 3-hydroxy-3-methylglutaryl-CoA to mevalonate in the pathway for cholesterol biosynthesis.

D. Increasing the rate of degradation of 3-hydroxy-3-methylglutaryl CoA reductase.

E. Stimulating the activity of the LDL receptor in the liver.

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

45. 15. The subcellular site of the breakdown of long chain fatty acids to acetyl-CoA via -oxidation is:

A. The cytosol

B. The matrix of the mitochondria

C. The endoplasmic reticulum

D. The mitochondrial intermembrane space

E. E.The Golgi apparatus

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

46. 16. A patient presents in your office with very high levels of serum cholesterol. He states that he has tried to follow the diet and exercise regimen you gave him last year. You decide that this patient would benefit from a drug such as Lipitor (atorvastatin). This class of drugs is effective in treating hypercholesterolemia because it has what effect?

A. A.Stimulates phosphorylation of the β-hydroxyl-β-methylglutaryl-CoA reductase enzyme

B. Decrease the stability of theβ-hydroxyl-β-methylglutaryl-CoA reductase protein

C. Binds cholesterol preventing it from being absorbed by the intestine

D. Directly prevents the deposition of cholesterol on artery walls

E. Inhibits the enzymeβ-hydroxyl-β-methylglutaryl-CoA reductase

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

47. 17. All of the following are derived from cholesterol except:

A. Bile salts

B. Progesterone

C. Glucocorticoids

D. Squalene

E. Mineralocorticoids

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

48. 18. A newborn infant had trouble breathing at birth. The infant was 3 months premature. The physicians treated the infant with a solution, which was directly injected into the lungs. Within seconds, the infant responded with much improved breathing. A major component of this solution is which one of the following?

A. Dipalmitoyl phosphatidylcholine

B. Palmitate containing ceramide

C. Sphingosine

D. Sphingomyelin

E. Diacylgylycerol

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

49. 19. Which one of the following statements about the absorption of lipids from the intestine is correct?

A. Dietary triacylglycerol is partially hydrolyzed and absorbed as free fatty acids and monoacylglycerol.

B. Dietary triacylglycerol must be completely hydrolyzed to free fatty acids and glycerol before absorption.

C. Release of fatty acids from triacylglycerol in the intestine is inhibited by bile salts.

D. Fatty acids that contain ten carbons or less are absorbed and enter the circulation primarily via the lymphatic system.

E. Formation of chylomicrons does not require protein synthesis in the intestinal mucosa

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

50. 20. The rate-limting enzyme in the β-oxidation of fatty acid is

A. acyl CoA synthetase

B. carnitine acyltransferase I

C. carnitine acyltransferase II

D. acyl CoA dehydrogenase

E. hydroxyacyl CoA dehydrogenase

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

51. 21. In humans, obesity is not caused by leptin levels, but by malfunctioning signal mechanisms. Which of the following do you think might be affected by high leptin concentrations binding to receptor?

A. Activation of acetyl CoA to malonyl CoA

B. Lipase

C. Phosphate pentose pathway

D. Cholesterol synthesis

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

52. 1. The primary manner for the deamination of amino acids in muscle involves.

A. purine nucleotide cycle

B. oxidative deamination of glutarate

C. transamination

D. ornithine cycle

E. conjunction of transamination and oxidative deamination

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

53. 2. The most important role of S-adenosyl methionine (SAM) is.

A. to provide methionine

B. to synthesize tetrahydrofolate

C. to synthesize purine nucleotides

D. to synthesize pyrimidine nucleotides

E. to supply methyl group

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

54. 3. When compared to his state after an overnight fast, a person who fasts for 1 week will have

A. higher levels of blood glucose

B. less muscle protein

C. more adipose tissue

D. lower levels of ketone bodies in the blood

E. none of the above

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

55. 4. Mr Smith had been prescribed a drug to treat his depression. One of the effects of the drug is to maintain elevated levels of a particular neurotransmitter that has been derived from which of the following amino acids?

A. Tryptophan

B. Tyrosine

C. Glutamate

D. Histidine

E. Glycine

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

56. 5. Which of the following are the nitrogen source of urea ?

A. carbomoyl phosphate and aspartate

B. carbomoyl phosphate and ornithine

C. α-amino group and γ-amino group of ornithine

D. α-amino group of citrulline and α-amino group of arginine

E. γ-amino group of ornithine and glycine

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

57. 6. Which of the following amino acids can be converted into taurine in the body?

A. Cysteine

B. Glycine

C. Methionine

D. Threonine

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

58. 7. Which of the following state is nitrogen equilibrium?

A. advanced cancer patient

B. pregnant women

C. patient recovering from illness

D. people suffer form long-time hunger

E. normal adult

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

59. 8. Which of the following is not produced by Tyr?

A. norepinephrine

B. epinephrine

C. dopamine;

D. Phe

E. melanin

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

60. 9. Which of the following is the main deamination style in the body?

A. oxidation deamination

B. reduction deamination

C. direct deamination

D. transamination;

E. union deamination

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

61. 10. Which of the following is the carrier of one carbon unit ?

A. biotin

B. SAM

C. FH4

D. FH2

E. folic acid

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62. 11. Which one of the following amino acids is essential in the human diet?

A. Serine

B. Lysine

C. Glutamate

D. Tyrosine

E. Cysteine

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

63. 12. The compound which does not belong to one carbon unit as follow is.

A. -CH3

B. =CH2

C. =CH-

D. CO2

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64. 13. Which of the following amino acid can not produce one carbon unit?

A. Serine

B. Valine

C. Tryptophan

D. Histidine

E. Glycine

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

65. 14. Which of the following state is positive nitrogen balance?

A. advanced cancer

B. pregnant women

C. people suffer from fever

D. people suffer form long-time hunger

E. normal adult

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

66. 15. Which of the following amino acid can produce PAPS?

A. taurine

B. methionine

C. cysteine

D. homocysteine

E. glutamate

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

67. 16. In the presence of hyperammonia, production of which of the following amino acids is always increased?

A. Glycine

B. Arginine

C. Proline

D. Histidine

E. Glutamine

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

68. 17. The major fate of ammonia is ( ) in the body.

A. to synthesize nonessential amino acids

B. to synthesize glutamine

C. to synthesize urea

D. to synthesize alanine

E. to synthesize nucleotides

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

69. 18. The transportation form of ammonia in blood is

A. Glutamate

B. Tyrosine

C. Glutamine

D. Glutathionine

E. Aspartate

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

70. 19. Which of the following is the process that transport ammonia from muscle to liver?

A. TAC cycle

B. ornithine cycle

C. alanine-glucose cycle

D. methionine cycle

E. γ-glutamyl cycle

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

71. 20. Which of the following is the direct donor of CH3?

A. N5-CH3-FH4

B. SAM

C. N5,N10- CH2-FH4

D. N5,N10=CH-FH4

E. FAD

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

72. 1. 男，51岁，近3年来出现关节炎症状和尿路结石，进食肉类食物时，病情加重。该患者发生的疾病涉及代谢途径是

A. 糖代谢

B. 脂代谢

C. 核苷酸代谢

D. 嘌呤核苷酸代谢

E. 氨基酸代谢

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

73. 2. 与体内尿酸堆积相关的酶是

A. 酰胺转移酶

B. 四氢叶酸还原酶

C. 转甲酰基酶

D. 黄嘌呤氧化酶

E. 磷酸核糖焦磷酸合成酶

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

74. 3. 体内嘌呤核苷酸的分解代谢终产物是

A. 尿素

B. NH

C. β－丙氨酸

D. β－氨基异丁酸

E. 尿酸

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

75. 4. 与抗代谢药5－FU化学结构相似的物质是

A. 腺嘌

B. 鸟嘌呤

C. 胸腺嘧啶

D. 尿嘧啶

E. 胞嘧啶

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

76. 5. 下列物质含量异常可作为痛风诊断指征的是

A. 嘧啶

B. 嘌呤

C. β－氨基异丁酸

D. 尿酸

E. β－丙氨酸

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

77. 6. 嘌呤从头合成的氨基酸有

A. 鸟氨酸

B. 谷氨酸

C. 天冬酰胺

D. 天冬氨酸

E. 丙氨酸

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

78. 7. 合成嘌呤、嘧啶的共同原料是

A. 甘氨酸

B. 天冬酰胺

C. 谷氨酸

D. 天冬氨酸

E. 氨基甲酰磷酸

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

79. 8. 在体内能分解生成β－氨基异丁酸的是

A. AMP

B. GMP

C. CMP

D. UMP

E. TMP

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

80. 9. 氢杂丝氨酸干扰核苷酸合成是因为它的结构类似于

A. 丝氨酸

B. 甘氨酸

C. 天冬氨酸

D. 天冬酰胺

E. 谷氨酰胺

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

81. 10. 干扰dUMP转变生成dIMP的是

A. 6巯基嘌呤

B. 甲氨蝶呤

C. 链霉素

D. 别嘌呤醇

E. 阿糖胞苷

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

82. 1. 以醋酸纤维素薄膜作支持物进行血清蛋白质电泳的缓冲液常用的pH为

A. 3.5

B. 5.5

C. 6.5

D. 7.5

E. 8.6

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83. 2. 在血浆蛋白电泳中，泳动最慢的蛋白质是

A. 清蛋白

B. a1－球蛋白

C. a2－球蛋白

D. B－球蛋白

E. －球蛋白

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

84. 3. 血浆蛋白质中含量最多的是

A. 清蛋白

B. α1－球蛋白

C. α2－球蛋白

D. β－球蛋白

E. γ球蛋白

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

85. 4. 具有氧化酶活性的是

A. 免疫球蛋白

B. 肌红蛋白

C. 脂蛋白

D. 铜蓝蛋白

E. 清（白）蛋白

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

86. 5. 转运游离脂肪酸的是

A. 免疫球蛋白

B. 肌红蛋白

C. 脂蛋白

D. 铜蓝蛋白

E. 清（白）蛋白

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

87. 6. 下列关于血红蛋白合成的叙述，正确的是

A. 以甘氨酸、天冬氨酸为原料

B. 只有成熟红细胞才能进行

C. 与珠蛋白合成无关

D. 受肾分泌的促红细胞生成素调节

E. 合成全过程仅受ALA合酶的调节

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

88. 7. 属于血红蛋白直接分解产物的物质是

A. 胆红素

B. 血栓素

C. 细胞色素c

D. 血红素

E. 胆素原

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

89. 8. 下列关于血红蛋白的叙述,错误的是

A. 是含有铁卟啉辅基的蛋白质

B. 存在紧张态和松弛态两种构象

C. 一个血红蛋白分子能与4个氧分子可逆结合

D. 是由4个亚基组成的具有四级结构的蛋白质

E. 其氧解离曲线与肌红蛋白相同,是直角双曲线

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

90. 9. 成熟红细胞不具有的代谢途径是：

A. 糖酵解

B. 磷酸戊糖途径

C. 三羧酸循环

D. 2,3-BPG支路

E. 氧化还原反应

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

91. 1. 发生在肝生物转化第二阶段

A. 葡糖醛酸结合反应

B. 氧化反应

C. 还原反应

D. 水解反应

E. 脂化反应

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

92. 2. 胆汁中含量最多的有机成分是

A. 胆色素

B. 胆汁酸

C. 胆固醇

D. 磷脂

E. 黏蛋白

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

93. 3. 属于次级非结合胆汁酸的是

A. 甘氨胆酸

B. 牛磺胆酸

C. 鹅脱氧胆酸

D. 牛磺鹅脱氧胆酸

E. 石胆酸

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

94. 4. 下列关于游离胆红素的叙述，正确的是

A. 胆红素与葡糖醛酸结合

B. 水溶性较大

C. 易透过生物膜

D. 可通过肾脏随尿排出

E. 与重氮试剂呈直接反应

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

95. 5. 下列哪种物质是结合胆红素？

A. 胆红素清蛋白

B. 胆红素－Y蛋白

C. 胆红素乙蛋白

D. 葡糖醛酸胆红素

E. 胆红素－结合珠蛋白

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

96. 6. 完全性梗阻性黄疸时，正确的是

A. 尿胆原（－）尿胆红素（－）

B. 尿胆原（＋）尿胆红素（－）

C. 尿胆原（－）尿胆红素（＋）

D. 尿胆原（＋）尿胆红素（＋）

E. 胆素（＋）

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

97. 7. 胆红素生成的限速酶是:

A. 单胺氧化酶

B. 血红素加氧酶

C. 胆红素加氧酶

D. 胆红素氧化酶

E. 胆素脱氢酶

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

98. 8. 下列哪一物质为初级结合胆汁酸？

A. 石胆酸

B. 牛磺胆酸

C. 脱氧胆酸

D. 鹅脱氧胆酸

E. 甘氨石胆酸

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

99. 9. 肝穿刺活检发现肝大．肝细胞内糖原颗粒累积，颗粒糖原分支处仍然保留单个葡萄糖残基，可能功能有缺陷的酶是

A. α1,4磷酸化酶

B. α1,4转移酶

C. 磷酸葡萄糖变位酶

D. α1,糖苷酶

E. 溶酶体α1,4糖苷酶

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

100. 10. Select the one of the following statements that is NOT CORRECT :

A. The Bohr effect refers to the release of protons that occurs when oxygen binds to deoxyhemoglobin.

B. Shortly after birth of the human infant synthesis of the α-chain undergoes rapid induction until it

C. The β-chain id fetal hemoglobin is present throughout gestation.

D. Thalassemias are genetic defects due to partial or total absence of the α- or β-chains of hemoglobin

E. The taut conformation of hemoglobin is stabilized by several salt bridges that form between the subunits.

答案：请关注【九八五题库】微信公众号，发送题目获取正确答案。

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